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Physical mapping, cloning, and identification of genes within a 500-kb region containing BRCA1.

机译：物理映射，克隆和鉴定包含BRCA1的500 kb区域内的基因。

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摘要

BRCA1 is a breast/ovarian cancer susceptibility gene on human chromosome 17q21. We describe a complete and detailed physical map of a 500-kb region of genomic DNA containing the BRCA1 gene and the partial cloning in phage P1 artificial chromosomes. Approximately 70 exons were isolated from this region, 11 of which were components of the BRCA1 gene. Analysis of the other exons revealed a rho-related G protein and the interferon-induced leucine-zipper protein IFP-35.

机译：BRCA1是人类17q21染色体上的乳腺癌/卵巢癌敏感性基因。我们描述了包含BRCA1基因的基因组DNA的500-kb区域的完整和详细的物理图谱，并在噬菌体P1人工染色体中部分克隆。从该区域分离出大约70个外显子，其中11个是BRCA1基因的组成部分。对其他外显子的分析显示，rho相关的G蛋白和干扰素诱导的亮氨酸拉链蛋白IFP-35。

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作者
Brown, M A; Jones, K A; Nicolai, H; Bonjardim, M; Black, D; McFarlane, R; de Jong, P; Quirk, J P; Lehrach, H; Solomon, E;
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年度 1995
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正文语种 en
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2. Physical mapping, cloning, and identification of genes within a 500-kb region containing BRCA1. [J] . Brown MA, Jones KA, Nicolai H, Proceedings of the National Academy of Sciences of the United States of America . 1995,第10期

机译：物理映射，克隆和鉴定包含BRCA1的500 kb区域内的基因。
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5. Physical-Chemical Quality of 'Cabernet Sauvignon' Clones in High Altitude Regions of Santa Catarina State, Brazil [C] . A.F. Brighenti, L. Rufato, A.A. Kretzschmar, International Horticultural Congress on Science and Horticulture for People . 2012

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7. Physical mapping cloning and identification of genes within a 500-kb region containing BRCA1. [O] . M A Brown, K A Jones, H Nicolai, 1995

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Physical mapping, cloning, and identification of genes within a 500-kb region containing BRCA1.

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